Prevalence of Benzodiazepine and Benzodiazepine-Receptor Agonist Use in a Geriatric Emergency Department Population
نویسندگان
چکیده
منابع مشابه
Differences in Benzodiazepine Receptor Agonist Use in Rural and Urban Older Adults
BACKGROUND Older adults are especially susceptible to adverse consequences of potentially inappropriate medications (PIMs), such as benzodiazepine receptor agonists (BZDRAs), due to age-related pharmacokinetic and pharmacodynamic changes. Although some risk factors for BZDRA use in older adults have been identified, the role of rural versus urban residence is less clear. OBJECTIVE To describe...
متن کاملThe Benzodiazepine Receptor
The 1,4-benzodiazepines have become the most frequently prescribed of all psychotropic drugs since the introduction of the first member of this series, chlordiazepoxide, into clinical practice in 1960. The compounds are used as anxiolytics, sedative/hypnotics, anticonvulsants, and muscle relaxants. This unique spectrum of activity, together with their large therapeutic index and essential lack ...
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OBJECTIVE To evaluate the association between use of benzodiazepines and incident dementia. DESIGN Prospective, population based study. SETTING PAQUID study, France. PARTICIPANTS 1063 men and women (mean age 78.2 years) who were free of dementia and did not start taking benzodiazepines until at least the third year of follow-up. MAIN OUTCOME MEASURES Incident dementia, confirmed by a ne...
متن کاملSolubilized benzodiazepine receptors for use in receptor assays.
In the development of non-radioactive receptor assays for benzodiazepines, employing fluorescent ligands, it was observed that the fluorescence measurements were hampered by the background fluorescence of the receptor preparation. This receptor preparation is a brain tissue homogenate in which the benzodiazepine receptors are membrane-bound. To minimize the influence of the receptor material on...
متن کاملBenzodiazepine use and driving: a meta-analysis.
OBJECTIVE The purpose of the present study was to examine the experimental and epidemiologic evidence linking benzodiazepine use to driving impairment. DATA SOURCES We searched MEDLINE, PsycINFO, the Cochrane Collaboration, and EMBASE using the key terms ("benzodiazepines" OR "exp benzodiazepines") AND ("automobile driving" OR "accidents, traffic" OR "driving" OR "driver$") and limited the re...
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ژورنال
عنوان ژورنال: Journal of the American Geriatrics Society
سال: 2019
ISSN: 0002-8614
DOI: 10.1111/jgs.15842